The following information may be applicable to you. Please ensure that the information in this leaflet is correct and that you have read all of the enclosed documents.
Nexium, manufactured by AstraZeneca, is a brand name for the medication esomeprazole. It is an acid-suppressing drug used to treat stomach ulcers and gastroesophageal reflux disease (GERD) in adults and children over 12 years old. Nexium is used to treat symptoms of heartburn and acid reflux caused by gastroesophageal reflux disease (GERD), such as heartburn and stomach pain, acid reflux and ulcers. Nexium is also used to treat symptoms of gastroesophageal reflux disease (GERD) when the body cannot take esomeprazole in sufficient quantities. This includes conditions such as GERD, heartburn and ulcers. Nexium works by reducing the amount of acid produced in the stomach by blocking the enzyme responsible for producing the acid. This helps to reduce symptoms of GERD, such as heartburn, acid reflux, heartburn, nausea, vomiting and stomach pain. If you have questions about this medication or want to talk to one of our pharmacists, please call us at.
To use Nexium, follow these steps:
Take Nexium by mouth as directed by your doctor, usually 1 to 3 times a day. If you do not have a doctor’s prescription, you can ask the local pharmacy or local healthcare provider for help.
The following drug interactions have been reported with this drug. Please see the "Drug interactions for Nexium" sections for additional information.
If you think you may have any of these conditions, please tell your doctor or pharmacist. These conditions may be life threatening and require immediate medical attention.
Do not take Nexium if you:
• Are allergic to esomeprazole or any ingredients of the medication
• Are taking medicines such as Zyrtec, lansoprazole or other prescription or nonprescription medicines, especially in a high-dose setting
• Have severe kidney problems or a history of these conditions
• Are pregnant or trying to become pregnant. Please tell your doctor or pharmacist if you are pregnant or breastfeeding.
Alternate Name:Pharmapure RX Esomep-EZS
Description:Nexium treats gastroesophageal reflux disease (GERD), esophagitis, and stomach ulcers. The generic version of Nexium is esomeprazole magnesium. For a supply of 30 oral tablets of Nexium Delayed-Release Capsules 40 mg is approximately $287. Take advantage of our LowerMyRx discount to receive a typical Nexium discount of up to 80% off of the retail price at participating pharmacies near you.
Dosage Form:Capsule Delayed Release
Administration Route:By mouth
Drug Class:Gastric Acid Secretion Inhibitor, Gastrointestinal Agent
Generic Available:Yes
Strength:20 MG
Warnings:Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, lupus, vitamin B12 deficiency, or osteoporosis. This medicine may cause the following problems: Kidney problems, including acute tubulointerstitial nephritisIncreased risk of broken bones in the hip, wrist, or spine (more likely if used several times per day or longer than 1 year)Serious skin reactions, including Stevens-Johnson syndrome, toxic epidermal necrolysis, acute generalized exanthematous pustulosis, and drug reaction with eosinophilia and systemic symptoms (DRESS)LupusFundic gland polyps (abnormal growth in the upper part of your stomach) This medicine can cause diarrhea. Call your doctor if the diarrhea becomes severe, does not stop, or is bloody. Do not take any medicine to stop diarrhea until you have talked to your doctor. Diarrhea can occur 2 months or more after you stop taking this medicine. Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results. Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments. Keep all medicine out of the reach of children. Never share your medicine with anyone. Stomach pain, nausea, vomiting, weight loss, bloody or black stools
Food Warnings:Do not use esomeprazole if you are also using medicines that contain rilpivirine., Some medicines can affect how esomeprazole works. Tell your doctor if you are using any of the following: Atazanavir, cilostazol, diazepam, digoxin, erlotinib, ketoconazole, methotrexate, mycophenolate mofetil, nelfinavir, rifampin, saquinavir, St John's wort, tacrolimus, voriconazoleBlood thinner (including clopidogrel or warfarin)Diuretic (water pill)Iron supplements, This medicine can cause diarrhea. Diarrhea can occur 2 months or more after you stop taking this medicine., Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results., Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments., Keep all medicine out of the reach of children.
This, of course, contains important information about Nexium. We do not recommend that you take Nexium 30 mg without talking to your doctor. Taking Nexium with food may increase the chance of a stomach upset. However, you should not take this medicine if you are using medicines that contain sucralfate, such as rilpivirine., Some medicines can affect how esomeprazole works. Tell your doctor if you are using any of the following: Zocor, digoxin, ergotamine, diuretics, laxatives, penicillin, proton pump inhibitors, St. John's wort, tacrolimus, voriconazoleBlood thinner (including clopidogrel or warfarin)Diuretic (water pill)Iron supplements, This medicine can cause diarrhea.Nexium 20 mg and Gastro-Resistant Pregame, known as "the tablet", are both proton pump inhibitors (PPIs) used to treat gastroesophageal reflux disease (GERD) and also Zollinger-Ellison syndrome.
Nexium is also indicated for the prevention and treatment of esophageal cancer.
Nexium is a newer-generation PPI developed by Novo Nordisk. It works by blocking the secretion of stomach acid from the gastric and duodenum. This action reduces gastric acid and duodenal secretion of food to relieve symptoms of gastro-oesophageal reflux disease.
Nexium is effective in managing symptoms associated with GERD, including heartburn, acid reflux, and regurgitation.
Nexium is sometimes used to treat other conditions related to the stomach and duodenum, such as:
Nexium's mechanism of action involves blocking the action of the enzyme that converts gastric acid to gastric acid, which decreases the release of gastric acid into the duodenum. This reduction in gastric acid helps reduce the symptoms of GERD, which is a common side effect of PPIs.
Nexium is also sometimes used in the management of duodenal ulcer disease. It helps reduce the frequency and severity of ulcers, and the risk of duodenal ulcer recurrence.
Nexium is effective in managing symptoms associated with duodenal ulcer disease. It also helps reduce the frequency and severity of gastrointestinal bleeding. It is also effective in preventing recurrence of gastric ulcers.
Nexium is often prescribed to treat conditions related to the stomach and the duodenum, such as:
Nexium is sometimes used to prevent the recurrence of liver disease. However, other conditions and diseases can occur with the use of Nexium.
It is important to note that Nexium may also reduce the risk of liver damage in certain patients. Patients who develop liver damage should discuss this risk with their healthcare provider.
Nexium works by blocking the action of the enzyme gastric and duodenal at the cellular level, which in turn can reduce the production of gastric acid and duodenal secreted by the stomach and duodenum.
Nexium blocks the action of gastric and duodenal at the cellular level to prevent the reabsorption of gastric acid into the intestine. This reabsorption prevents the absorption of food into the stomach and prevents the reabsorption of food into the duodenum.
Inhibition of gastric and duodenal enzymes results in a decrease in gastric acid production and reduced gastric secretion of food by reducing gastric and duodenal secreted by the stomach and duodenum.
What is Reflux?
Reflux is the backflow of acid from the stomach into the gullet (“foodpipe”) which may become inflamed and painful. This may cause you symptoms such as a painful sensation in the chest rising up to your throat (heartburn) and a sour taste in the mouth (acid regurgitation).
Do I get instant relief from taking a Nexium tablet?
Nexium Control is not meant to bring immediate relief. You may need to take the tablets for 2-3 days in a row before you feel better. You must talk to a doctor if you do not feel better or if you feel worse after 14 days.
How much to take• The recommended dose is one tablet a day. • Do not take more than this recommended dose of one tablet (20 mg) a day, even if you don’t feel an improvement immediately. • You may need to take the tablets for 2 or 3 days in a row before your reflux symptoms (for example, heartburn and acid regurgitation) get better. • The treatment length is up to 14 days. • When your reflux symptoms have completely gone you should stop taking this medicine. • If your reflux symptoms get worse or do not improve after taking this medicine for 14 days in a row, you should consult a doctor. If you have persistent or longstanding, frequently recurring symptoms even after treatment with this medicine, you should contact your doctor. Taking this medicine • You can take your tablet at any time of the day either with food or on an empty stomach. • Swallow your tablet whole with half a glass of water. Do not chew or crush the tablet. This is because the tablet contains coated pellets, which stop the medicine from being broken down by the acid in your stomach. It is important not to damage the pellets.
Alternative method of taking this medicine• Put the tablet in a glass of still (non-fizzy) water. Do not use any other liquids. • Stir until the tablet breaks up (the mixture will not be clear) then drink the mixture straight away or within 30 minutes. Always stir the mixture just before drinking it. • To make sure that you have drunk all of the medicine, rinse the glass very well with half a glass of water and drink it. The solid pieces contain the medicine – do not chew or crush them
Please read the patient information leaflet above to get more information as to side effects, precautions of use etc.
Active Ingredients:
Each gastro-resistant tablet contains 20 mg esomeprazole (as magnesium trihydrate)
List of Excipients:
Glycerol monostearate 40-55 HydroxypropylcelluloseHypromellose 2910 (6 mPa-s) Reddish-brown iron oxide (E-172) Yellow iron oxide (E-172)Magnesium stearate Methacrylic acid ethylacrylate copolymer (1: 1) dispersion 30 per cent Cellulose microcrystallineSynthetic Paraffin Macrogol 6000Polysorbate 80 Crospovidone (Type A) Sodium stearyl fumarateSugar spheres (sucrose and maize starch), Talc, Titanium dioxide (E-171) Triethyl citrate
Stereosole (Nexium Control) Nexium Control Stenosef (Nex-S) Nexium Control Stenosef 20mg (Nex-T 20 mg) Esomeprazole 20mg (Nex-T 20 mg) Talc 20mg (Nex-T 20 mg) Titanium dioxide (E-171) Triethyl citrate 2.5 mg/100 mlTitanium dioxide (E-171)corn Starch, Sodium lauryl sulfate, Sodium starch glycolate, Saturated fatty alcohol, Sodium laurilsulfate, Sodium stearyl fumarateSodium bicarbonatePolysorbate 80 Croscarmel 10.
Stade de France Pharmacy